Pharmacokinetic studies are used to demonstrate bioavailability and
bioequivalence of veterinary products in the target animals. We have the experience
and expertise to design, carry out and report all necessary pharmacokinetics
studies. For the interpretation of results, our experts use our specialist pharmacokinetics
and statistics software, and prepare expert reports. They also establish relationship
of pharmacokinetic data to MICs as needed for anti-infectives
Metabolism studies provide valuable information for the assessment of the potential
risks to man and target animal species.
These investigations include the identification of the marker residues in edible
tissues, milk or eggs, which will be defined as the residues to be quantified
in subsequent residue studies used to derive Maximum Residue Limits (MRLs).
This work can involve the identification of previously unknown metabolites in
the matrix of concern, using techniques such as LC/MS/MS.
We have extensive experience in the use of radiolabelled compounds in conducting
absorption, distribution, metabolism and excretion (ADME) studies in target
animals. We can also offer to synthesise radiolabelled test substances.
At Huntingdon Life Sciences, our Department of Large Animal and Avian Studies
provides an extensive and fully equipped range of accommodation for farm and
companion animals, adaptable for either group or individual housing.
- Cattle, lactating dairy cows, sheep, goat
- Poultry: chickens, turkeys, ducks
- Pigs
- Cats, dogs, rabbits and small companion animals
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