ADME and Dermal Penetration

Ecotoxicology

Environmental fate

Genetic Toxicology

Field trials

Mammalian Toxicology

Metabolite Identification

Physical Chemical Properties

Plant and Livestock Metabolism

Regulatory Affairs

Residue Analysis

Synthesis

In vitro Techniques

Programme Management and Consultancy

 

Plant and livestock metabolism

These studies are critical to the human risk assessment for crop protection products. Their purpose is to fully evaluate the nature of the residue, in terms of parent active substance and metabolites, that may occur in foodstuffs intended for human or animal consumption. The data are used to define the residue to be determined in residue field trials or livestock feeding studies.

The rotational or succeeding crop metabolism study is specifically aimed at investigating the nature of the residue (if any) that may occur in crops grown in the same soil following a crop that has been treated with the active substance.

Studies offered include:

  • Plant metabolism and rotational crop metabolism. We have experience with many crops including:
    • Cereals: wheat, barley, maize, rice
    • Fruit: apple, orange, grapefruit, grape, olive, strawberry, melon, tomato, cucumber, aubergine (egg plant)
    • Leafy crops: cabbage, lettuce and other vegetables
    • Roots and tubers: potato, sugar beet, carrot, turnip
    • Pulses and oilseeds: oilseed rape, soya bean, cotton, pea, bean
  • Livestock metabolism: species include lactating and beef cattle, lactating goats, pigs, sheep and laying hens
  • Nature of the residue resulting from processing
  • Identification of metabolites

We can offer to synthesise radiolabelled test substances that are always required for plant and livestock metabolism studies.